Amazing Health Benefits of Green Tea.

Health benefits of green tea and risks associated with consuming green tea so as a brief introduction green tea comes from the leaves of the plant camellia sinensis green tea is composed of the following this is according to dry

weight proteins and enzymes make up 15 to 20 percent amino acids make up one to four percent carbohydrates make up five To seven percent methylxanthines including caffeine make up about three to four percent in some sources say two to five percent fiber makes up 26% and polyphenols so flavonoids like catechins make up approximately 30 percent so again this is by dry weight and this is dry weight of a green tea leaf so it’s catechins that I really want to talk about cadogan’s are what seem to be responsible for the health effects of Green tea.

the most abundant catechin is actually a catechin known as epic gallo catechin three dallied or EGCG so catechins are actually in other foods and other drinks a green tea is actually the dietary source with the highest level of catechins and it actually has the highest amount of antioxidants compared to other teas as well and these antioxidants mediate many of the green teas health effects as well so you can see here that green tea has a lot of Catechins and also has high amount of antioxidants both of which can mediate health effects.

health benefits so it’s not surprising that green tea has been associated with many health benefits so we’re going to talk about these in this lesson but as we will see later on in this lesson there are also health risks associated with green tea consumption specifically consumption of green tea

supplements which we will talk about later on in this lesson so the Information presented here in this slide comes from this review entitled beneficial effects of green tea a literature review so before I get into talking about the health benefits and health risks of green tea the disclaimer here is that most of this evidence comes from in vitro data or in vitro studies which means that it was done in cell culture in a petri dish so only in certain cell lines so it’s not done in humans and some other data

That was done in an models like mice so we don’t see many of these studies being performed in humans so that is the disclaimer before we go on further so the first thing I want to talk about with regards to green tea and health benefits is its antibacterial effects EGCG that catechin that is most abundant in green tea has been shown to have antibacterial properties there’s actually evidence for activity against the following again this evidence is in In vitro studies so the first one is actually helical bacter pol ory we see it done in this study here green tea inhibits he’ll go back to claw regrowth in vivo and in vitro there’s also evidence for EGC G’s activity

against streptococcus mutans streptococcus mutans is a bacteria we find in our mouth and we actually see in this study entitled camellia sinensis or tea invitations in role in preventing dental decay that EGCG has activity against Streptococcus mutans so it can actually possibly prevent dental decay the question is does green tea consumption prevent dental caries or dental cavities so that is interesting

evidence EGCG has also been found to have activity against ecoli so there’s a question of is it an effective treatment for UTI so this study was actually performed in humans so there’s some evidence in vitro that EGCG and other components of green tea have negative inhibitory effects on e Coli and they also looked at the urinary excretion of green tea in humans and they actually found that green tea was excreted in the urine so there is this question of does green tea through its excretion in the urine could this be a possible treatment for e.coli and Ecola is an important bacteria that can often cause a UTIs there’s also been some evidence showing that green

tea may have modulatory effects on multi drug-resistant bacteria like Staphylococcus aureus and we see that in this article here and green tea also seems to promote the effect of some antibiotics some of these include tetracycline and carbapenems and these articles are the references so EGCG seems to enhance the activity of tetracycline especially in staphylococci bacteria by inhibiting the flux of tetracycline

from the bacterial cell so it can promote tetracycline activity to help treat the infection and green tea And EGCG has been shown to help modulate some activity of kharap enemies to help treat beta lactam resistant staphylococci infections as well so the next set of health benefits from green tea include

the possible antiviral effects from green tea consumption there have actually been multiple in vitro studies that have demonstrated antiviral properties of eg CG so a lot of what I’m gonna be showing here talking about here comes from these two articles one a Review article entitled a review of the antiviral role of green tea catechins which was published in 2017 the other article here is an older one entitled inhibition of adenovirus infection in adenine by green tea catechins so this was published in 2003 so from those two articles there have been evidence mostly in vitro there have been some evidence in vivo as well but in animal models but mostly in vitro that

EGCG inhibits hepatitis B virus infections inhibits Hepatitis C virus can inhibit HSV or herpes simplex virus EBV HIV adenovirus influenza virus 5e viruses like dengue virus rotaviruses and intra viruses so again all of this evidence doesn’t necessarily say that these are very very significant effects and they are also in vitro in certain cell lines so again there are many many details here in those review articles that

I mentioned here that wouldn’t be easily covered in this lesson so if you want more Information on these in vitro studies please check out those review articles I mentioned here and slide there are also possible anti my Kotik effects of green tea consumption so anti mycotic means it’s antifungal so there’s actually been some evidence showing activity against Candida albicans we can see in this article entitled antifungal efficacy of green tea extract against Candida albicans biofilm onto

substrate and green tea Seems to improve antifungal efficacy as well so this article entitled multiple effects of green tea catechins on the antifungal activity of anti my cot –ax against Candida albicans so it seems that green tea may improve or increase the activity of some antifungals like amphotericin be against Candida albicans infections so again interesting

vitro in vivo and epidemiological studies demonstrating anti-cancer and anti metastatic properties of green tea again most of these are in vitro and in vivo and in vivo means in a live organism but those live organisms are mice often times so one study here that we’ll talk about is green tea inhibits vascular endothelial growth factor veg F induction in human breast cancer cells another is effects of catechins on the Mouse lung carcinoma cell adhesion to the endothelial cells and most of it will be coming from this review article entitled cancer and metastasis prevention and treatment buying green tea so what we can gather from those articles is that green tea

has been shown to have hibbett ori effects on skin cancers like melanoma prostate cancer breast cancer lung cancer liver cancer colorectal cancer so again these are all showing Some in vitro evidence so again in a cell culture dish that there may be some inhibitory anti-cancer effects from green tea on these types of cells on these types of cancer cells some of these also have been shown to possibly have an associated

decrease risk in some individuals who commonly consumed green tea again it’s an association so we can’t completely tell that green tea is actually inhibiting or preventing cancer or reducing the risk of cancer so again Very important to take away from the slide there’s also some evidence that green tea may have some positive effects in chronic diseases so green

reduce neurotoxicity induced by beta amyloid as we noted in that article there so these articles all lead to certain questions as green tea decrease The risks of Ellmers disease does green tea improve conditions like Parkinson’s disease and as green tea have a neuro protective mechanism that is meted by activation of etaf adji so that one of those articles I mentioned here shows that green tea can activate etapa G does it lead to

neuro protective mechanism we’re not sure yet there’s also some evidence to support that green tea may have some beneficial effects on cardiovascular disease so green tea may Reduce risk cardiovascular disease it is a disclaimer again because a lot of this evidence is in vitro so does green tea reduce the risk of ischemic heart disease so we can see in this article here tea consumption and risk of ischemic heart

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disease that there may be some protective effects and more notably and more specifically catechins may reduce cardiovascular disease by the following they’ve been shown to have the Following effects so the following effects are from this article here entitled green tea catechins and cardiovascular health and update one of them is that

catechins may prevent formation of atherosclerosis another is catechins seem to reduce cholesterol levels through inhibition of squalene epoxidized so squealing EPOXI days is an enzyme in the cholesterol synthesis pathway inhibition of squalene epoxies would lead to decreased Cholesterol synthesis catechins may also reduce triglyceride levels after eating through inhibition of pancreatic lipase and phospholipase a2 it may prevent platelet aggregation and activation and catechins seem to inhibit vascular inflammation by preventing leukocyte adhesion to the endothelium some other possible health

benefits of green tea include anti-obesity effects so this may be due to changes in gut microbiota so this article entitled green tea Polyphenols decrease weight gain ameliorate alteration of met microbiota and mitigate intestinal inflammation in canines with high-fat diet induced obesity so with onset of obesity comes changes in gut microbiota and at least in dogs green tea seems to prevent or slow down the change in gut microbiota that occurs so this could be related to what may happen in humans as well there also seems to be anti photoaging effects green tea antioxidants are known to Neutralize reactive oxygen species that are produced from UV rays so there the question is as green tea have an anti-wrinkle effect so this article here entitled the review of the role of green tea in anti photoaging stress resistance neural protection and etapa G we mentioned this article before this also talks about anti photo aging so green tea in the context of anti photo aging doesn’t necessarily have to be from Consumption of green tea but it could be from topical green tea administration so if you were to put green tea creams on this may show some help with anti photo aging or anti wrinkle effect again some of the state is very preliminary so we now move on to health risks of green tea not everything about green tea is beneficial so it’s actually been shown that high levels of EGCG may be cytotoxic again a lot of these studies are in vitro in in other animal models Some in vitro studies have shown the following regarding high EGCG it may cause hepatocellular damage especially when consuming green tea extract or supplements so this has actually been shown in some news articles and news findings where individuals who are trying to be healthy start taking green tea supplements and have liver failure because they take too much so we see in this article entitled features and outcomes of 899 patients with Drug-induced liver injury the the il I end prospective study supplement that was used that caused liver injury was actually green tea supplements or green tea extract so they actually could see increases in liver enzyme so showing liver damage but we don’t seem to see this with normal consumption of just plain green tea so if you were to drink green tea we don’t see the same effect so because of this possible effect on the liver it’s Probably important to avoid green tea extract in supplements high levels of EGCG may also cause damage to pancreatic beta-cell DNA and we see in this animal model study in instructors of Tosun induced diabetic rats and EGCG may cause enlargement of the thyroid gland it may cause a goiter you can see it in this article here entitled goitrogenic effects of green tea extract catechins by dietary administration in rats again.

Another Animal a lot of times these are in animal models except for that study I mentioned before with regards to the hepatocellular damage or the liver damage so what are some of the other possible health risks of green tea consumption so green tea leaves can absorb large amounts of aluminum and consuming large amounts of aluminum can actually lead to unsafe

aluminum intake and eventually lead to anemia or low Blood count so unsafe aluminum levels can actually lead to anemia so this is actually presented in this article entitled the role of aluminum in the pathogenesis of anemia in an outpatient hemodialysis population so that is another possible health effect of green tea consumption so

Again a lot of possible beneficial health effects but there’s also some health risks with regards to green tea consumption and there are so many other studies on Health benefits and health risks of green tea that I likely missed something in this lesson so if I did please leave it in the comments below and I hope you found this lesson helpful and informative if you did please give it a thumbs up and consider subscribing to the channel and as always thank you so much for watching and I hope to see you next time